Welcome to Habitat For Horses!|Saturday, July 4, 2015

Equine Study: Lower Corticosteroid Doses Might be Beneficial 

corticosteroids and horses





Anyone who has used corticosteroids for themselves or their horse knows that these medications come with some much unwanted side effects. However, these drugs can be essential to helping your horse overcome pain and inflammation when other methods don’t work. This is why continued research in equine medicine is so important. Check with your vet if your horse is taking corticosteroids. ~ HfH

From: The Horse
By: Frank Angst

corticosteroids and horses

“We need a dose large enough for efficacy but small enough to avoid cell death,” MacLeod said of the recommended dosage.
Photo: Anne M. Eberhardt

Initial results of a study conducted at the University of Kentucky Gluck Equine Research Center suggest accepted dosage levels for several commonly used corticosteroids might be worth further study.

At the Kentucky Equine Drug Research Council’s (KEDRC) regular meeting March 12 in Lexington, Jamie MacLeod, VMD, PhD, John S. and Elizabeth A. Knight chair and professor of veterinary science at the Gluck Equine Research Center, outlined initial results of a study that looked at the efficacy and dangers of methylprednisolone, betamethasone, and triamcinolone, which are used to treat ailing joints in racehorses.

The study concluded that the desired therapeutic effects of the corticosteroid treatments, especially methylprednisolone and betamethasone, could be accomplished at lower dosage levels than recommended by the manufacturer and commonly used on the backstretch. MacLeod said as dosage levels increase, more negative side effects were observed.

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